Showing posts with label Francis Collins. Show all posts
Showing posts with label Francis Collins. Show all posts

Friday, May 26, 2017

Health and Business Execs Make the Case for NIH Funding

A chalkboard message that reads, "Invest in your health."
Photo credit: Shutterstock
At a time when the White House has been flirting with the idea of slashing billions from the budget of the National Institutes of Health, a group of executives, government officials, and academic leaders recently went to Washington, D.C. to make the case for the NIH’s continued funding.

The meeting, organized by General Atlantic CEO William E. Ford, involved 27 people, including NIH Director Francis Collins, Vice President Mike Pence, nine White House officials, and a cadre of top names in the academic and biotech worlds.

In case you’re not familiar with what the NIH does, it’s basically the largest biomedical research agency in the world. Its team of scientists does research on treating and preventing chronic diseases, curing infectious diseases, using new medical technologies to promote wellness, and healthy aging. The agency also provides grants to researchers at universities and other academic institutions. In other words, the NIH is a pretty important part of the U.S. health infrastructure.

Although Congress granted the NIH a $34 billion budget for 2017, Trump’s proposed “skinny budget” for the fiscal year 2018 (which begins in October 2017) reduces the NIH’s budget by $5.8 billion.

The point the White House visitors were trying to make is that private investment is not an adequate substitute for the NIH’s support for research at colleges and universities. They also said the odds of winning NIH funding for that research are getting slimmer and slimmer because the organization’s budget has stayed flat for years.

The group worries that Trump’s immigration policies are making it harder to recruit foreign scientists as well. University of Texas heart disease researcher Helen Hobbs said her Chinese postdocs are now taking jobs in China rather than staying in the U.S.

“Federal support for fundamental science in academia is the driver of national innovation, leading to new medicines that improve quality of life and longevity and make major contributions to job and economic growth,” said Stanford University President Richard P. Lifton. “Biotechnology took off in this country because of U.S. leadership in federal support for science. Our system is the envy of the world.”

Collins tried to drive the point home by noting how funding the NIH will check two boxes on Trump’s priority list: jobs and the healthcare budget.

Their tag-team approach may have had the desired effect. According to Ford, the two-hour meeting went well. “The members of the new administration we met with were very receptive to our message, and I’m confident that a productive dialogue has begun,” he said.

Chan Zuckerberg Initiative President of Science Cori Bargmann agreed. “The message in the room was heard loud and clear: We need the NIH! And we need it now more than ever,” she wrote in a Facebook post just after the meeting.

People may have emerged from the meeting optimistic, but nobody talked about the elephant in the room—the proposed cuts to NIH’s 2018 budget.

Are the NIH’s funding prospects going to improve because of the meeting?  “I think time will tell,” Collins said.


Friday, July 10, 2015

The New York Genome Center Uses DNA Research to Develop Personalized Cancer Treatments

human genome model, dna model for research
NYGC is at the forefront of research into the human genome, or the complete set of nucleic acid sequence encoded as DNA.
Image: Shutterstock
The New York Genome Center (NYGC) is at the forefront of research into the human genome. Leaders in technology, science, and medicine form this consortium. Their goal is to combine genomic data and industrial innovation into treatments for people suffering from serious disease. Business leaders like NYGC Board of Directors member William Ford, CEO of General Atlantic, provide the insight and experience required to discover, build, and maintain productive partnerships.

Each human cell contains our genome. Composed of DNA, the genome contains instructions for making our bodies. Strands of DNA form chromosomes, found in the nucleus of each cell. Our genes are sections of DNA within our chromosomes and control traits like eye color and height. The human genome is made of 3.2 billion bases of DNA. Enough data to fill a stack of paperback books reaching 200 feet high.

Vast amount of scientific research into cancer is being conducted and published each year. “The real challenge before us is how to make sense of massive quantities of genetic data and translate that information into better treatments for patients,” said Robert Darnell, M.D., Ph.D., CEO, President and Scientific Director of the NYGC.

Traditionally an oncologist searching for a DNA-based treatment for a patient’s specific type of cancer would have to invest crushing amounts of time and money coordinating reams of data to find the right treatment. Luckily the clouds have parted and there is hope on the horizon. That hope is based on the cloud computing capacity of IBM Watson working in partnership with the NYGC’s data. “Applying the cognitive computing power of Watson is going to revolutionize genomics and accelerate the opportunity to improve outcomes for patients with deadly diseases by providing personalized treatment.”

The Human Genome Project (HGP) completed the mapping of the human genome n 2001. This data provides detailed information about the structure and organization of a complete set of human genes. "It's a shop manual, with an incredibly detailed blueprint for building every human cell. And it's a transformative textbook of medicine, with insights that will give health care providers immense new powers to treat, prevent and cure disease," said Francis Collins, director of the National Human Genome Research Institute.


For more information about the New York Genome Center and the innovative work it does, visit www.nygenome.org.
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